489.Which of the following syndrome is characterized by multiple large 'cold staphylococcal abscesses?

    1.Job's syndrome       
    2.Lazy leukocyte syndrome.      
    3.Chediak-higashi syndrome.    
   4.Wiskott Aldrich syndrome.           
ANS- Job's syndrome         
Reference : -  Ananthnarayan-157

488.The occurrence of hyperthyroidism following administration of supplemental iodine to subjects with endemic iodine deficiency goitre is known as:

  1.Jod-Basedow effect    
  2.Wolff-Chaikoff effect     
  3.Thyrotoxicosis factitia     
  4.De Quervain's thyroiditis

Ans-1. Jod-Basedow effect  
   
  Reference : - > Harrison-(15)-2077

485. Thiamine deficiency causes decreased energy production because

 a) It is required for the process of transamination.
 b) It is co-factor in oxidative reduction .
c)It is co-enzyme for transketolase in pentose phosphate pathway .
d) It is co-enzyme for pyruvate dehydrogenase.

Ans-d) It is co-enzyme for pyruvate dehydrogenase.

484. Reactive arthritis is caused by

 a) Staph. aureus
b) H. influenza
c) N. gonnorhea
d)  E.coli

Ans-c) N. gonnorhea

483. which drug does not metabolize by acetylation:

 a)Isoniazid
 b)Metaclopromide
 c)Procainamide
 d)Dapsone

Ans-b.Metoclopramide

482.Which of the following is a derivative of the second pharyngeal arch?

A. Eustachian tube
B. External auditory meatus
C. Palatine tonsil
D. Stylohyoid muscle
The correct answer is D. The stylohyoid is derived from the second pharyngeal arch, which also
gives rise to the muscles of facial expression, the stapedius, the posterior belly of the digastric
muscle, Reichert's cartilage, and the facial nerve.

481.During a cranial nerve test, the patient cannot elevate her right eye from the abducted position. Which of the following muscles is paralyzed?

A. Right inferior oblique
B. Right inferior rectus
C. Right lateral rectus
D. Right superior oblique
E. Right superior rectus
The correct answer is E. The superior rectus muscle can elevate and adduct the eye from the
neutral position. From the abducted position, it is the only muscle that can elevate the eye.
The inferior oblique muscle (choice A) can elevate and abduct the eye from the neutral position.
From the adducted position, it is the only muscle that can elevate the eye.
The inferior rectus muscle (choice B) can depress and adduct the eye from the neutral position. From
the abducted position, it is the only muscle that can depress the eye.
The lateral rectus muscle (choice C) can abduct the eye.
The superior oblique muscle (choice D) can depress and abduct the eye from the neutral position.
From the adducted position, it is the only muscle that can depress the eye

480.Hirschsprung's disease indicates a developmental abnormality in which of the following embryonic tissues?

 A. Ectoderm
B. Endoderm
C. Neural crest
D. Neural ectoderm

Ans-c.Neural crest

The baby has Hirschsprung's disease, which is due to an absence of
ganglion cells in the wall of the colon. Neural crest cells contribute to the formation of many adult
structures. Among these are all of the postganglionic neurons of the autonomic nervous system and
the sensory neurons of the peripheral nervous system.

479.At which of the following ages does fetal movement first occur?

A. 1 month
B. 2 months
C. 4 months
D. 6 months

Ans-B.2months
Neuromuscular development is sufficient to allow fetal movement in the
eighth week of life. Other features of Week 8 include the first appearance of a thin skin, a head as
large as the rest of the body, forward-looking eyes, appearance of digits on the hands and feet,
appearance of testes and ovaries (but not distinguishable external genitalia), and a crown-rump length
of approximately 30 mm. By the end of the eighth week, nearly all adult structures have at least begun
to develop, and the fetus "looks like a baby.

478 :Bleeding joints is a characteristic feature of:

  1. Vitamin C deficiency.
  2. Hemophilia.  
  3. Vitamin K deficiency. 
  4. Thrombocytopenia.

Ans-2.Hemophilia

477:Auspitz’s sign is seen in:

  A. Lupus erythematosus 
  B Pemphigold  
  C. Lichen planus 
  D. None of the above

   Ans-D.None of the above

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