470.All potentiate digoxin toxicity except

a.Hyperkalemia
b.Hypomagnesia
c.Hypercalcemia
d.Renal failure

Ans-a.Hyperkalemia
 Ref-Katzung pg 54-55   10th ed
Hyperkalemia is a protective factor as in the presence of hyperkalemia,the binding of digoxin becomes less

442.Drug of choice for epilepsy in pregnancy

a.Carbamezipine
b.Sodium valproate
c.Phenobarbitone
d.Phenytoin


Ans-c.Phenobarbitone

441.Which of the following intravenous induction agent is the most suitable for day care surgery

a.Morphine
b. Ketamine
c.Propofol
d.Diazepam

Ans-Propofol

440.Which of the following inhalational agent is the induction of choice in children

a.Methoxyflurane
b.Sevoflurane
c.Desflurane
d.Isoflurane


Ans-Sevoflurane

439.First dose hypotension is caused by

a.Prazosin
b.Clonidine
c.Sodium nitroprusside
d.Propanol


Ans-Prazosin

320.A 50 year old woman with end stage renal disease develops pulmonary tuberculosis.which one of the following should be used in reduced dose

a.Rifampicin
b.Pyrazinamide
c.Isoniazid
d.Ethambutol

Ans-d.Ethambutol

317.Ipatropium bromide is contraindicated in

a.Urinary retention
b.Asthma
c.Hypertension
d.All

Ans-a.Urinary retention
refer -KDT 6th ed pg 110

316.Forced alkaline diuresis of alkalinization of urine is used in poisoning with

a.Barbiturates
b.Amphetamine
c.Alcohol
d.Datura
Ans-a.Barbiturates
Explanation -refer KDT 6th ed pg 13,392

310.For which of the following dose adjustement is not required in case of liver cirrhosis

a.Lorazepam
b.Theophyline
c.PCM
d.Metronidazole

Ans-a.Lorazepam

Ref Katzung 10th ed pg 985

242.All of the following drugs causes hyperkalemia except

a.NSAIDS
b.Heparin
c.Amphotericin B
d.cyclosporine

Ans-c.Amphotericin B

238.Which one of the following anaesthetic agents causes a rise in the intracranial pressure?

a.Sevoflurane
b.Thiopentone sodium
c.Lignocaine
d.Propofol

Ans-a.Sevoflorane

Explanation-Intracranial pressure increases at high inspired concentrations of Sevoflorane.Ref Aitkinhead 4th/159

236.Anaesthetic agent of choice in renal and hepatic failure

a.Doxacurium
b.Tubocurarine
c.Pancuronium
d.Atracurium

Ans-d.Atracurium


Isoflorane is also the anaesthetic of choice in renal and hepatic failure
Ref K.D.Tripathi 5th ed pg 314

229.Drug of choice to treat hypertension during pregnancy

a.Diuretics
b.Enalapril
c.Reserpine
d.Methyldopa

Ans-d.Methyldopa

Explanation:Ref K.D Tripathi 5th ed pg 517

227.Name the drug having rapid onset despite high pka (9.1)

a.Procaine
b.Tetracaine
c.Chloroprocaine
d.Bupivacaine

Ans.c.Chloroprocaine

Explanation:Ref KDT 6TH ed pg 353

226.Drug not used in acute asthma is:

1.Salbutamol.
2.Ipratropium.
3.Montelukast.
4.Hydrocortisone.

Ans:3.Montelukast.

Explanation:KDT 5th ed pg 205

214.Cross resistance of isoniazid is not seen with

a.Rifampicin
b.Ethionamide
c.Cyclosporine
d.Ethambutol

Ans:b.Ethionamide


Explanation:Ref katzung 10/ed pg 772

213.Filgastrim is used in treatment of

a.Anaemia
b.Neutropenia
c.Malaria
d.Filarial

Ans:b.Neutropenia

Explanation:Filgastrim is a recombinant human granulocyte colony stimulating factor effective in the treatment of severe neutropenia.It mainly stimulates CFU-g to increase neutrophil production.(Ref Goodman &Gillman 11/ed pg 1440

56.Lysis of fibrin is brought about by:

A. Plasmin B. Hyaluronidase
C. Collagenase D. Coagulase


Answer is: A- Plasmin. (Ref. K.D. Tripathi-5th )



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