24.Heart failure cells are seen in the following condition

1. CVC lung b.CVC liver c.CVC spleen
   

Ans.(a): Refg. 185/2nd Harish mohan

-CVC of lung occurs in test heart failure especially in rheumatic mitral stenosis so that there is consequent rise in pulmonary venous pressure.

-Histologically the breakdown of erythrocytes liberates haemosiderin pigment which is taken up by alveolar macrophages, so called heart failure cells, present in the alveolar lumina.

-CVC of liver occurs in right heart failure

-cut surface shows “nutmeg liver”.

-microscopically centrilobular haemorrhagic necrosis may be seen.

-CVC of spleen seen in right heart failure

-microscopically gamna-gandy bodies (or) syderofibrotic nodules are seen.

Ref.286/harshamohan.

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